Triple Marker Test
The triple marker test, also known as the triple screen test, is a prenatal screening test used to evaluate the risk of certain chromosomal abnormalities and neural tube defects in the fetus. It typically measures the levels of three substances in the mother’s blood:
- Alpha-fetoprotein (AFP): AFP is a protein produced by the fetus and is normally found in the mother's blood during pregnancy. Abnormal levels of AFP may indicate an increased risk of neural tube defects such as spina bifida or anencephaly.
- Human chorionic gonadotropin (hCG): hCG is a hormone produced by the placenta during pregnancy. Abnormal levels of hCG may be associated with an increased risk of chromosomal abnormalities such as Down syndrome (trisomy 21) or Edwards syndrome (trisomy 18).
- Estriol: Estriol is a hormone produced by both the fetus and the placenta during pregnancy. Abnormal levels of estriol may also be associated with an increased risk of chromosomal abnormalities.